3,4 Dimethoxybenzaldehyde Veratraldehyde 99 Percent Chemical Intermediate CAS 120 14 9

3,4-Dimethoxybenzaldehyde (CAS 120-14-9), widely recognized as Veratraldehyde, is a high-purity aromatic aldehyde specifically optimized for use as a pharmaceutical intermediate. Supplied as a white to off-white crystalline powder with a minimum assay of 99%, it functions as a fundamental building block in the synthesis of several essential active pharmaceutical ingredients, notably including antihypertensive therapies and indole alkaloids. Its consistent quality, well-defined reactivity, and reliable performance in sensitive synthetic pathways make it a trusted choice for API manufacturers and fine chemical producers.

• Pharma-Grade Purity:

  Minimum 99% assay ensures high conversion efficiency and minimizes by-product formation in multi-step synthetic sequences, reducing downstream purification requirements.

• Predictable Reactivity:

  The aldehyde functionality enables reliable condensation and reduction reactions, allowing for efficient construction of complex molecular frameworks essential for therapeutic activity.

• Consistent Crystalline Form:

  Supplied as a white to off-white crystalline powder with a stable melting point, allowing precise weighing and predictable dissolution behavior in standard pharmaceutical process solvents.

• Regulatory Traceability:

  Fully documented with CAS 120-14-9 and accompanied by a comprehensive Certificate of Analysis, supporting drugs master file submissions and quality management system compliance.

• Scalable Supply:

  Manufactured under controlled conditions to ensure batch-to-batch uniformity, guaranteeing reproducibility from laboratory development through pilot scale to full commercial production.

• Antihypertensive API Synthesis

  The primary pharmaceutical application of Veratraldehyde is as the key intermediate in the manufacture of centrally acting antihypertensive agents. It undergoes condensation with nitroethane or similar C2 synthons, followed by reduction and resolution, to yield therapeutically active compounds used in managing hypertension, particularly in sensitive patient populations.

• Indole Alkaloid Synthesis

  Veratraldehyde serves as an essential starting material for synthesizing indole alkaloids prescribed as antihypertensive and antipsychotic agents. It provides the dimethoxyphenyl fragment that is incorporated into the polycyclic framework through established cyclization sequences, contributing critical structural features required for biological activity.

• Heterocyclic Scaffold Construction

  The aldehyde group allows the formation of Schiff bases, hydrazones, and various heterocyclic ring systems. These structural motifs are prevalent in medicinal chemistry programs targeting a range of therapeutic areas, making Veratraldehyde a versatile synthon in both early-stage discovery and established commercial processes.

• Specialty Fine Chemical Synthesis

  Beyond pharmaceutical applications, Veratraldehyde is employed as a precursor in the preparation of high-value compounds where a substituted benzaldehydecore is required, offering a reliable entry point for constructing complex organic molecules.

• Optimized for API Manufacturing:

  Our 99% purity grade is specifically controlled to limit impurities that could interfere with critical reduction or condensation steps, ensuring higher yields and lower purification costs.

• Stringent Quality Assurance:

  Each batch undergoes rigorous testing and is accompanied by a detailed Certificate of Analysis. Full traceability and documentation support your regulatory submissions and quality system requirements.

• Technical and Process Support:

  Our team includes chemists with direct experience in pharmaceutical intermediate synthesis who can provide guidance on handling, storage, and reaction optimization, helping you improve process robustness and troubleshoot scale-up challenges.

• Secure and GMP-Conscious Packaging:

  Packed in pharmaceutical-grade fiber drums with inner liners to prevent contamination during transit and storage. Custom packaging sizes, labeling, and inert atmosphere sealing are available to meet specific production line and cleanroom requirements.

• Global Logistics with Full Documentation:

  We provide complete documentation packages and leverage extensive experience in international chemical logistics to ensure timely, safe, and compliant delivery to your facility worldwide.